Tuesday, December 31, 2019

Symbolism in Sonnys Blues by James Baldwin Essay

Symbolism in â€Å"Sonny’s Blues† by James Baldwin In James Baldwin’s â€Å"Sonny’s Blues,† the reader meets Sonny, a recovering addict, and his older brother, a high school teacher. Although these two brothers have completely different lives and personalities, the author’s use of symbolism brings them more tightly together like a real family. Baldwin uses symbols such as ice, lightness and darkness, and jazz music to add more depth and meaning to â€Å"Sonny’s Blues.† People usually think of ice or the cold as being bitter and causing discomfort. When it is cold outside, people wear jackets to eliminate the bitterness of the cold. In â€Å"Sonny’s Blues,† Sonny uses heroine to escape the discomfort of the reality that is his life. Heroine is Sonny’s†¦show more content†¦Another symbol that Baldwin uses throughout the story is the symbol of lightness and darkness. Lightness and darkness usuall y symbolize good and evil. One example of darkness that Baldwin uses in â€Å"Sonny’s Blues† is when Mama, the narrator’s mother, was telling him about the death of his and Sonny’s uncle. After Mama told the story of the brothers’ uncle being run over and killed by a car full of white men, she said, â€Å"Your Daddy says he never in his life seen anything as dark as that road after the lights of that car had gone away† (58). In this example, Baldwin uses the darkness of the road to create a deeper meaning behind the uncle’s death and the father’s sadness. The reason the father felt as if nothing could ever be as dark as that road is because he experiences his only brother dying in front of him. Death, especially murder, is considered to be a very â€Å"dark† subject. When there is a funeral, mostly every person is wearing black or dark clothing because he is mourning over the death of a loved one. Another example is when the narrator reminisces on the days when all of the ‘old folks’ would sit around in the living room after church. â€Å"They would all sit in the chairs while the night is creeping up outside, but no one knows it yet†¦everyone is looking at something a child cannot see† (56). Baldwin uses the darkness of night as a symbol of death in thisShow MoreRelatedSymbolism And Themes In Sonnys Blues By James Baldwin1958 Words   |  8 PagesWhile reading â€Å"Sonny’s Blues† by James Baldwin theme, symbolism, and motifs were discovered throughout the entire short story. Sonny one of the two main characters, is dealing with a drug addiction and is now following his dreams of becoming a jazz musician. The narrator, whose name was never given, does his best to keep the promise he made his mother years ago, to be his brother’s keeper. James Baldwin, an African American author, grew up in Harlem, New York. Baldwin had no one to share his loveRead MoreThe Themes Of Symbolism In Sonnys Blues By James Baldwin1590 Words   |  7 PagesSonny’s Blues by James Baldwin is a short story that expresses the themes of alienation, identity, drugs, music, family, suffering, redemption, racism in society and imprisonment. Baldwin uses a lot of symbolism, allegories and imagery within the text. Music, alienation, drugs and suffering are the themes that are most clearly understood and show up the most. Music and drugs and perfect examples of symbolism. And when Baldwin talks about suffering and alienation they have the closest connection toRead MoreLiterary Analysis of â€Å"Sweat† and â€Å"Sonny’s Blues†1549 Words   |  7 PagesLiterary Analysis of â€Å"Sweat† and â€Å"Sonny’s Blues† Amelia Williams ENG125: Introduction to Literature Instructor: Deborah Zeringue December 22, 2014 As living and breathing human beings people are bound to experience some type of conflict. Conflict can be present within a person, between two people, between a person and forces of nature, and even between a person and their society. Conflict is defined as the struggle that shapes the plot in a story (Clugston, 2014, ch.4sect.1 para.4). When readingRead MoreRacism In Sonnys Blues By James Baldwin993 Words   |  4 Pagesonly seems to be progressing into something that one simply cannot comprehend. In the short story â€Å"Sonny’s Blues,† the author, James Baldwin, emphasizes the lasting effect of racism throughout the story. While Baldwin vaguely expresses the impact of racial bias on the character Sonny, the audience infers the idea the author is trying to convey. In the story, racism is a significant factor of symbolism portrayed through the overall hometown setting, key events told throughout the story, and the overallRead MoreRacism In Sonnys Blues By James Baldw in935 Words   |  4 Pagesto be progressing into something that one simply cannot comprehend. In the short story â€Å"Sonny’s Blues,† the author, James Baldwin, emphasizes on the lasting effect of racism throughout the story. Baldwin vaguely expresses the impact of racial bias on the character Sonny. The audience has to infer the reasoning behind what the author is trying to convey. In the story, racism is a significant factor of symbolism portrayed through the overall hometown setting, key events told throughout the story, andRead MorePoint of View and Symbolism in Sonnys Blues1558 Words   |  7 PagesPoint of View and Symbolism in â€Å"Sonny’s Blues† The story â€Å"Sonny’s Blues† by James Baldwin makes excellent use of multiple literary elements. Namely, I think the writer utilizes symbolism and the nuances of point of view to give the story a deeper connotation that could not be said plainly. The meat of the story is about an unnamed older brother’s relationship and differences with his younger brother, Sonny. Sonny’s aspiration to become a jazz pianist leads him in an opposite direction than hisRead MoreSonny s Blues By James Baldwin827 Words   |  4 PagesSonny’s Blues In James Baldwin’s â€Å"Sonny’s Blues† it is only when a brother loses his child that he realizes how easy it can be to lose his brother. The narrator’s little brother, Sonny, was left in his charge when their parents passed away. He neglects Sonny and leaves him to work through hard decisions on his own which leads to Sonny being picked up by the police for using and selling drugs. When the narrator’s daughter, Grace, passes he sees how suffering can affect people and reaches outRead More Symbolism in James Baldwins Sonnys Blues Essay1242 Words   |  5 PagesSymbolism in James Baldwins Sonnys Blues Missing Works Cited Several passages found throughout Sonnys Blues indicate that as a whole, the neighborhood of Harlem is in the turmoil of a battle between good and evil. The narrator describes Sonnys close encounters with the evil manifested in drugs and crime, as well as his assertive attempts at distancing himself from the darker side. The streets and communities of Harlem are described as being a harsh environment which claims the lives ofRead MoreMovie Analysis : Sonny s Blues1248 Words   |  5 PagesHopeless Records Some people might agree that a broken home might be better then no home, or maybe having no home is better then having a hopeless home. The narrator who is unnamed in Baldwin’s â€Å"Sonny’s Blues†, is from a home that you can carry good and horrid memories with you. In the short story â€Å"Sonny’s Blues†, the narrator along with his entire household all have personal suffering that affect their lives tremendously. Consider that almost everyone has problems in their life and household, weatherRead MoreLiterary Canon Of The 21st Century1637 Words   |  7 Pagesthe midst of all those great literature works, there are some great standing out articles due to their strong composition and meaningful life messages that the authors try to convey to the audiences. One of them is the short story â€Å"Sonny’s Blues†, written by James Baldwin in 1957. This story shows us the reality as well as the complexity of life matters, and an overall pi cture of all the subcategories also really shows us the reason why it should be remained as a part of the literary canon of the 21st

Sunday, December 22, 2019

Harmful Effects of Smoking - 2429 Words

Harmful Effects Of Smoking Smoking isnt good for ones body. Especially if youve been smoking a pack a day, and for a long period of time. But what is the full extent of the effects of smoking on your body? The effects of smoking varies from person to person as it will depend on the persons vulnerability to the chemical in cigarette or tobacco smoke. It will also depend on the number of cigarette sticks a person smokes per day, the age when the person first started to smoke, and the number of years the person has been smoking. According to recent studies, every year hundreds of thousands of people all over the globe die from medical complications caused by smoking. Aside from the stench it leaves on ones clothes, breath, and hair, it†¦show more content†¦Smoking is one of the biggest single causes of preventable disease and premature death in a large number of mainly developed countries around the world. In the UK around 120,000 people die each year from smoking-related diseases. 50% of long-term smokers die prematurely from smoking, a large number of them when they reach middle age. Globally around 2.5 million people die each year from smoking and it has been estimated that some time during the 2020s the number of deaths caused by smoking will hit the 10 million mark. The majority of people who die from smoking will have suffered from one of three main diseases: lung cancer, coronary heart disease or chronic obstructive pulmonary disease (COPD). Around 90% of all lung cancer deaths are caused from smoking and smoking is also the biggest risk factor for a number of other types of cancer as well. Overall, smoking has been linked to a third of all deaths from cancer. In the US, 1 in every 4 people die of cancer and over half a million people die each year from this disease. To give you a clearer idea, more than 1,500 people a day die from cancer. People who smoke a lot of cigarettes a day are particularly at risk of developing cancer and if those people have been smoking for a long time, the risk is even higher. For example, a person who has been smoking one packet of cigarettes a day for 30 years is more at risk than a person who has been smokingShow MoreRelatedThe Harmful Effects Of Smoking And Smoking1380 Words   |  6 Pagestime they light a smoke. Some of the harmful effects of smoking include various potentially lethal diseases to the smoker and others exposed to secondhand smoke, the sinful addiction caused by a key ingredient in cigarettes, and social issues smoking causes for smokers and their loved ones. Smoking should be prohibited completely because of the harmful physical and social effects it has on smokers and the non-smokers they associate with. First of all, smoking creates a number of health problems forRead MoreHarmful Effects of Smoking806 Words   |  4 PagesSmoking has become very common and fashionable, especially among young boys. This habit usually begins at school when boys try to experiment with every new thing that they can lay their hands on. Despite the warnings given by doctors about the ill-effects of smoking, people continue to smoke. Smokers are addicted to it, and even if they want to, they cannot refrain from picking up a cigar or cigarette and puffing away. Some youngsters smoke for the sake of society and some feel that would make themRead MoreHarmful Effects of Smoking1418 Words   |  6 PagesHarmful effects of smoking Doan Thi Huong Thao BAIU08155 International University HCMC Academic English 2 Bien Thi Thanh Mai Instructor May 17, 2010 Abstract Smoking is known to be a primary cause of harmful effects on health, family, environment and society. However, scientist research in health and environment, that researches show that smoking cause many diseases, even lung cancer. An aim of my study has been to determine that smoking also effect on family and society. Results indicatedRead MoreThe Harmful Effects Of Smoking Tobacco1547 Words   |  7 Pages The Harmful Effects of Smoking Tobacco My purpose for writing this paper is to educate the reader of the harms and effects done onto a person from smoking Tobacco and persuade anyone thinking about or attempting to smoke Tobacco to consider the following for your own benefit. I will cover most harmful effects Tobacco has on not only the person using it but also the people around them. I will also show both sides of the argument with both the pros and the cons of smoking Tobacco as well as provideRead MoreThe Harmful Effects Of Smoking Cigarettes964 Words   |  4 PagesTobacco is widely used by people around the world. It’s so addicting that many people cannot prevent themselves from smoking. The reason is because of a toxin called nicotine. Nicotine can be found in all tobacco products. Prior to research, researchers have found that nicotine changes the way the brain works, also when a person smokes tobacco they not only consume nicotine, but also over 600 chemicals including tar, ammonia, acetone, lead, methano l, and more (What s In a Cigarette?). Many ofRead More Harmful Effects Of Smoking Essay1907 Words   |  8 Pagespeople die because of lung cancer or other tobacco related illnesses. Everyone in the world comes in contact with smoke from a cigarette at least once in their lifetime, whether it is at a restaurant or at work. Millions of people are addicted to smoking, and thousands more become addicted every year. Cigarettes and other tobacco products are everywhere. Most of the addicted smokers started when they were young (Roberts 18). The reason why people get addicted to any type of tobacco product isRead MoreSmoking Life Away: The Harmful Effects of Smoking Cigarettes1403 Words   |  6 PagesSmoking Life Away Smoke travels far. After the smoke is released, it diffuses and travels in the atmosphere reaching just about anything at a reasonable distance. When one smoker puffs out, it affects that person, somebody across from that person, and the clean air around that person. Ever wonder why warnings and disclaimers are always present with anything that concerns smoking? This is because it is dangerous, and it is harmful , and it should warn you about the lasting impact it leaves youRead MoreEssay on Harmful Effects Of Smoking Cigarettes1247 Words   |  5 PagesHarmful Effects Of Smoking Cigarettes Mentioned Photos Not Included There are numerous effects of smoking Cigarettes that affect the individual. They can affect not only your health but also your social and family life. It can also affect the non-smoker around you. Non-smokers suffer from allergies, noise and eye irritations and headaches as a result of inhaling second hand smoke. Smoking while youre pregnant can result to the growth of the foetus and may even result in the death of the babyRead MoreShould Smoking Be Banned Harmful Effects On Individuals And The Economy1498 Words   |  6 Pages Smoking- A Costly and Deadly Habit One of the most common problems today that are killing people all over the world is smoking. Stress, personal issues, and high blood pressure are many reasons why people start this horrible habit. One cigarette leads to another which then can lead to major addiction. When someone smokes a cigarette they are not only hurting themselves, but others around them. Smoking causes people to be exposed to hazardous fumes and chemicals in many places. The habit of smokingRead MoreSecondhand Smoke Essay807 Words   |  4 PagesSecondhand smoke is just as harmful as smoking because it leads to a higher prevalence of cancer and heart disease, it affects children’s health, and harms nonsmokers since they are healthy. You ever thought if smoking was harmful to you or your friends? Is smoking really that good? Many years smoking has been proven to be harmful. Smoking takes control of your mind, body and physical appearance sometimes. Many smokers are starting to smoke now at a young age. Sm oking isn’t only harmful to you but all the

Saturday, December 14, 2019

Importance of Colloidal Dispersion in Pharmacy Free Essays

Importance of colloidal dispersion in pharmacy Pharmaceutical Applications of colloids: Colloids are extensively used for modifying the properties of pharmaceutical agents. The most common property that is affected is the solubility of a drug . However, colloidal forms of many drugs exhibits substantially different properties when compared with traditional forms of these drugs. We will write a custom essay sample on Importance of Colloidal Dispersion in Pharmacy or any similar topic only for you Order Now Certain medicinals have been found to possess unusual or increased therapeutic properties when formulated in the colloidal state. Another important pharmaceutical application of colloid is their use as drug delivery system. The most often used colloid type drug delivery systems include hydrogels, microspheres, microemulsions, liposomes, micelles, nanoparticles and nanocrystals. Here we mention the main characteristics of each colloidal delivery system. Hydrogels: Hydrogel is a colloidal gel in which water is the dispersion medium. It (also called aquagel) is a network of polymer chains that are hydrophilic, sometimes found as a colloidal gel in which water is the dispersion medium. Hydrogels are highly absorbent (they can contain over 99% water) natural or synthetic polymers. Hydrogels also possess a degree of flexibility very similar to natural tissue, due to their significant water content. These hydrogels have the ability to sense changes of pH, temperature, or the concentration of metabolite and release their load as result of such a change Natural and synthetic hydrogels are used for wound healing, as scaffolds in tissue engineering, and as sustained- release delivery systems. When used as scaffolds for tissue engineering, hydrogels may contain human cells to stimulate tissue repair, since they are loaded with pharmaceutical ingredients, hydrogels provide a sustained drug release. Light-sensitive, pressure- responsive, and electro-sensitive hydrogels also have the potential to be used in drug delivery. Environmentally sensitive hydrogels include slow response time, limited biocompatibility, and biodegradability. Hydrogel used as sustained-release drug delivery systems. it provide absorption, desloughing and debriding capacities of necrotics and fibrotic tissue. ydrogels that are responsive to specific molecules, such as glucose or antigens can be used as biosensors, as well as in DDS. Also used in disposable diapers where they â€Å"capture† urine, or in sanitary napkins, contact lenses (silicone hydrogels, polyacrylamides). Medical electrodes using hydrogels composed of cross-linked polymers (polyethylene oxide, polyAMPS and polyvinylpyrrolidone). hydrogel used as water gel explosives, rectal drug delivery and diagnosis. Other, less common uses include, breast implants, granules for holding soil moisture in arid areas, dressings for healing of burn or other hard-to-heal wounds. Wound gels are excellent for helping to create or maintain a moist environment, reservoirs in topical drug delivery; particularly ionic drugs, delivered by iontophoresis (see ion exchange resin), Common ingredients are e. g. polyvinyl alcohol, sodium polyacrylate, acrylate polymers and copolymers with an abundance of hydrophilic groups. Natural hydrogel materials are being investigated for tissue engineering; these materials include agarose, methylcellulose, hyaluronan, and other naturally derived polymers. However if the achievements of the past can be extrapolated into the future, it is likely that responsive hydrogels with a wide array of desirable properties will be forthcoming. Microparticles: Microparticles are small loaded microspheres of natural or synthetic polymers. Microparticles was initially developed as carriers for vaccines and anti-cancer drugs. More recently, novel properties of Microparticles have been developed to increase the efficiency of drug delivery and improv e release profiles and drug targeting. Several investigations have focused on the development of methods of reducing the uptake of the nanoparticles by the cells of the reticuloendothelial system and enhance their uptake by the targeted cells. Functional surface coatings of non-biodegradable carboxylated polystyrene or biodegradable poly (D,L- lactide-co-glycolide) microspheres with poly(L-lysine)-g-poly (ethylene glycol) (PLL-g-PEG) were investigated in attempts to shield them from nonspecific phagocytosis and to allow ligand- specific interactions via molecular recognisition. It was found that coatings of PLL-g-PEG- ligand conjugates provided for the specific targeting of microspheres to human blood- derived macrophages and dendritic cells while reducing non- specific phagocytosis. Microparticles can also be used to facilitate nontraditional routes of drug administration. It was found that Microparticles can be used to improve immunization using the mucosal route of administration of therapeutics. It was found in this study that mucosal route of administration of therapeutics can translocate to tissues in the systemic compartment of the immune system and provoke immunological reactions. Micro Nano-Emulsions: Microemulsions are excellent candidates as potential drug delivery systems because of their improved drug solubilization, long shelf life, and ease of preparation and administration. Three distinct Microemulsions- oil external, water external, and middle phase- can be used for drug delivery, depending upon the type of the dug and the site of action. In contrast to Microparticles, which demonstrate distinct differences between the outer shell and core, microemulsions are usually formed with more or less homogeneous particles. Microemulsions are use for controlled release and targeted delivery of different pharmaceutics agents. For instance, microemulsions were used to deliver oligonucleotides (small fragments of DNA) specifically to ovarian cancer cells. In contrast to microemulsions, Nanoemulsions consist in very fine oil-in-water dispersions, having droplets diameter smaller than 100 nm. Compared to microemulsions, they are in a meta stable state, and their structure depends on the history of the system. Nanoemulsions are very fragile systems. The nanoemulsions can find applications in skin care due to their good sensorial properties (rapid penetration, merging textures) and their biophysical properties (especially their hydrating power). Liposomes: Liposomes consist of an outer uni – or multilamellar membrane and an inner liquid core. In most cases liposomes are formed with natural or synthetic phospholipids similar to those in cellular plasma membrane, because of this similarity, liposomes are easily utilized by cells. Liposomes can be loaded by pharmaceutical or other ingredients by two principal ways: Lipophilic substances can be associated with liposomal membrane, and hydrophilic substances can be dissolved in the inner liquid core of liposomes. To decrease uptake by the cells of the reticuloendothelial system and/or enhance their uptake by the targeted cells, the membrane of liposomes can be modified by polymeric chains and/or targeting moieties or antibodies specific to the targeted cells, because they are relatively easy to prepare, biodegradable, and non- toxic, liposomes have found numerous applications as drug delivery systems. Liposomes are of colloidal dimensions and are preferentially taken up by the liver and spleen. Hence, principle of colloids is also used in targeted drug delivery system. Liposomes are used for drug delivery due to their unique properties. A liposome encapsulates a region on aqueous solution inside a hydrophobic membrane; dissolved hydrophilic solutes cannot readily pass through the lipids. Hydrophobic chemicals can be dissolved into the membrane, and in this way liposome can carry both hydrophobic molecules and hydrophilic molecules. To deliver the molecules to sites of action, the lipid bilayer can fuse with other bilayers such as the cell membrane, thus delivering the liposome contents. By making liposomes in a solution of DNA or drugs (which would normally be unable to diffuse through the membrane) they can be (indiscriminately) delivered past the lipid bilayer. There are three types of liposomes – MLV (multilamellar vesicles) SUV (Small Unilamellar Vesicles) and LUV (Large Unilamellar Vesicles). These are used to deliver different types of drugs. Liposomes are used as models for artificial cells. Liposomes can also be designed to deliver drugs in other ways. Liposomes that contain low (or high) pH can be constructed such that dissolved aqueous drugs will be charged in solution (i. e. , the pH is outside the drug’s pI range). As the pH naturally neutralizes within the liposome (protons can pass through some membranes), the drug will also be neutralized, allowing it to freely pass through a membrane. These liposomes work to deliver drug by diffusion rather than by direct cell fusion. Another strategy for liposome drug delivery is to target endocytosis events. Liposomes can be made in a particular size range that makes them viable targets for natural macrophage phagocytosis. These liposomes may be digested while in the macrophage’s phagosome, thus releasing its drug. Liposomes can also be decorated with opsonins and ligands to activate endocytosis in other cell types. The use of liposomes for transformation or transfection of DNA into a host cell is known as lipofection. In addition to gene and drug delivery applications, liposomes can be used as carriers for the delivery of dyes to textiles, pesticides to plants, enzymes and nutritional supplements to foods, and cosmetics to the skin. Another interesting property of liposomes is their natural ability to target cancer. The endothelial wall of all healthy human blood vessels is encapsulated by endothelial cells that are bound together by tight junctions. These tight junctions stop any large particles in the blood from leaking out of the vessel. Tumour vessels do not contain the same level of seal between cells and are diagnostically leaky. This ability is known as the Enhanced Permeability and Retention effect. Liposomes of certain sizes, typically less than 200 nm, can rapidly enter tumour sites from the blood, but are kept in the bloodstream by the endothelial wall in healthy tissue vasculature. Anti-cancer drugs such as Doxorubicin (Doxil), Camptothecin and Daunorubicin (Daunoxome) are currently being marketed in liposome delivery systems. Micelles: Micelles are similar to liposomes but they do not have an inner liquid compartment. Therefore they can be used as water- soluble biocompatible micro containers for the delivery of poorly soluble hydrophobic pharmaceuticals. Similar to liposomes their surface can be modified with antibodies (immunomicelles) or other targeting moieties providing the ability of micelles to specifically interact with their antigens. One type of micelles pluronic block copolymers, are recognized as pharmaceutical excipients listed in the U. S and British Pharmacopoeia. They have been extensively used in a variety of pharmaceutical formulations including delivery of low molecular mass drugs, polypeptides, and DNA. Furthermore, Pluronic block copolymers are versatile molecules that can be used as structural elements of polycation- based gene delivery system. Nanoparticles: Nanocapsules are sub-microscopic colloidal carrier systems composed of an oily or an aqueous core surrounded by a thin polymer membrane. Nanoparticles are the colloidal particulate systems with size ranging between 1-1000 nm. Based on the arrangement of drug and polymer matrix, nanoparticles can be classified into two types: nanospheres and nanocapsules . In nanospheres, rugs are either adsorbed or entrapped inside the polymeric matrix. In nanocapsules, drugs are confined to the inner liquid core while the external surface of nanoparticles is covered by the polymeric membrane. polymeric nanoparticles have gained considerable attention as potential drug delivery systems due to its targetability to particular organ/tissue and ability to deliver protein and peptide via oral route. Nanoparticles for drug delivery are generally ma de up of biocompatible and biodegradable polymers obtained from either natural or synthetic source. Natural polymers include chitosan, albumin, rosin, sodium alginate and gelatin while, synthetic polymers include poly (lactic acid) PLA, poly (D, L-glycolide), poly (lactide-co-glycolide), poly (caprolactones) (PCL) and poly (cyanoacrylates). The kinetics of drug release from nanoparticles depends on the strength of hydrophobic interactions between the polymer and drug and polymer degradation rate. The uptake and distribution of nanoparticles depend on its size. Nanoparticles of size ~10 nm are utilized for extended circulation, while ~100 and ~200 nm particles are utilized for passive targeting and intracellular drug delivery respectively. Though nanoparticles have many advantages over other conventional drug delivery systems certain properties like surface hydrophobicity and surface charge needs to be altered so as to increase the uptake of nanoparticles into cells. This can be done by judiciously manipulating the use of polymers. Coating the nanoparticles with chitosan which is positively charged significantly enhances the uptake and modulates the drug efflux of anticancer agents. Moreover, attachment of poly (ethylene glycol) moieties to the surface of nanoparticles increases the hydrophilicity and hence decreases the uptake by macrophages. Recent studies by Yoncheva et al. concluded that amino-pegylated poly (methyl vinyl ether-co-maleic anhydride) nanoparticles were able to cross the cell membrane of the absorptive enterocytes in a better way. Nanoparticles are characterized by a variety of techniques such as dynamic light scattering (DLS), electron microscopy (TEM or SEM), atomic force microscopy (AFM), Fourier transform infrared spectroscopy (FTIR), x-ray photoelectron spectroscopy (XPS), powder X-ray diffraction (XRD), matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF), and magnetic resonance (NMR). Two technologies can be used to develop such Nanocapsules: the interfacial polymerization of a monomer or the interfacial nano deposition of a performed polymer. Solid lipid nanoparticles are developed at the beginning of the 1990’s as an alternative carrier system to emulsions, liposomes, and polymeric nanoparticles. They are used in particular in cosmetic and pharmaceutical formulations. A novel nano-particle based drug carrier for photodynamic therapy has been developed. This carrier can provide stable aqueous dispersion of hydrophobic photo-sensitizers; yet preserve the key step of photo generation of singlet oxygen, necessary for photodynamic action. Nanoparticles have also found applications as nonviral gene delivery systems. Advantages of nanoparticles a) Longer shelf-stability b) High carrier capacity c) Ability to incorporate hydrophilic and hydrophobic drug molecules d) Can be administered via different routes e) Longer clearance time f) Ability to sustain the release of drug ) Can be utilized for imaging studies h) Increase the bioavailability of drugs i) Targeted delivery of drugs at cellular and nuclear level j) Development of new medicines which are safer k) Prevent the multi-drug resistance mediated efflux of chemotherapeutic agents l) Product life extension Nanocrystals: Inorganic crystals that interface with biologic systems have recently attracted widespread interest in biology and medicine. To explore the feasibility of in vivo target ing by using semiconductor quantum dots (qdots), which are small ( How to cite Importance of Colloidal Dispersion in Pharmacy, Papers

Friday, December 6, 2019

Caltex Australia Limited Free-Samples for Students-Myassignment

Question: Write a Report on a Company currently listed on the Australia Stock Exchange [ASX]. Answer: Introduction This is an oil company that has grown from humble beginnings and it has currently become Australias leading company in terms of transport fuels and it supplies almost one third of the entire fuel needs in Australia (RET, p 15). They provide safe and reliable supply of fuel that is of high quality using a flexible supply chain of fuel. This covers a great number of customer segments which may include aviation, agriculture, retailing, automotives, mining etc. close to 85% of this companys stores are operated by franchisees and thus its among the largest in terms of franchisors and retailers (AIP, p 3). Background information The history of this company began many years ago when Ampol which is an all-Australian oil importer was initially listed on the ASX around late 1940s. Refineries were opened by both Caltex and Ampol in the years 1950s and 1960s and these led to a fierce competition between the two companies in the arenas of service station and oil product industries (Smith, p 31). This company i.e. Caltex Australian company deals in oil products and services. All its decisions are made entirely by the board of management present in Australia. The company has close to 3,500 employees distributed and working across the entire country. Business organization Type of business organization This company is publicly listed on the ASX. This is indicated on the website and its where I got the information (https://www.asx.com.au/asx/research/listedCompanies.do?coName=C). This company i.e. Caltex Australian company operates entirely in Australia. The company was incorporated in the late 1960s however it eventually merged up with Ampol in 1995 and since then it has existed as Caltex Australian Company (Warrell, p 4). Location of the business The companys headquarters are in Market street Sydney New South Wales and it has branches in major states in Australia. The distribution network is well rooted in Australia and may include diesel stops, depots, marine facilities etc. each state has a Caltex station and also some of the locations that are remote (Caltex, 2017). Management and leadership Leadership The board of directors is composed of quite experienced leaders and they include Greig Gailey who is a non executive independent chairman. He has extensive experience in the oil industry and hes also well experienced in management duties in the areas of capital and industrial intensive industries (AMWU, p 3). Julian Segal the managing director and has great experience in managing big companies. Trevor Bourne is a non-executive independent director and he also has management experience which is very broad in the capital and industrial industries. Melinda Conrad has experience in strategy and governance. Steven Gregg, Bruce Morgan, Barbra Ward and Penny Winn directors are all experienced in terms of strategic governance and management. SWOT analysis of management The management of this company is composed of experienced leaders whose aim is to ensure the services provided by the company are satisfying to the clients. The managers are elected on professional merit and this is the reason as to why the company has performed well in Australia for decades (Michael, P 21). SWOT analysis table for Caltex Company in Australia Despite being the leading company in provision of oil services in Australia Caltex still has some weaknesses and threats to iron out. However, it thrives on many strengths and opportunities (Caltex, 2017). Strengths Good distribution infrastructure Good team of service provision Good management system and service provision Opportunities Venturing and opening stations in neighboring countries Investing more in current technology for improved services Adopting a 24 hour service provision idea Weaknesses Leaving all the decision to be made by top management Too much work place flexibility may encourage laxity Less focus on gender equality Threats Competition from other oil investors Stealing of oil by scrupulous employees Fluctuations in the forex exchange rates Role of Information and Communication Technology Caltex as a company in Australia has adopted the use of information and technology is ensuring its business keeps up with current trends in the 21st century. It has adopted the use of internet, modern advertisement platforms such as television and app adverts in smart phones to make its services and fuel prices known to its customers (Tilley, p 2). Communication among its managers is of current technology via emails, video conferences Skype etc. Online marketing has been used widely by this company to grow its roots in Australia. For example, recently Caltex chose Fujitsu as the main business technology service provider and the company has done this to ensure that it gives Caltex a competitive advantage that is ongoing (Australian Government, P 126). It does this by delivering innovations and service improvements in all the Caltex stations. It ensures incorporation of technology that is of best practise and couples this with consulting services that are of leading edge technology. Wi th such kind of technology adoption there is no doubt the company will continue commanding a big place in the fuel industry. Conclusion Caltex Company is one of the renowned fuel companies in Australia. The company is best known for good service delivery and it has been a leading company for many years since its inception. Its success is mainly attributed to the good management practises within the top management where people are employed on professional merit. The company leadership also has the interest of its employees at heart and it offers them much flexibility at work thus good service delivery. However, a few weaknesses and strengths as listed above have to be dealt with and rectified for the company to continue leading other investors in the fuel industry. Such challenges include attraction that is indigenous, and also ensuring gender equality. Recommendations The company should work on ensuring gender equality at work place is embraced The company should embrace the culture of involving some employees in the decision making process and not just leave that entirely to the top management. Work flexibility is encouraged in the working environment however some limits should be set so as this freedom does not interfere with service delivery to the clients References Department of Resources, Energy and Tourism (RET), Submission 18, p. 15. Tilley J(2012). AIP, Committee Hansard, Canberra, 30 November 2012, p. 2. Australian Manufacturing Workers Union (AMWU), Submission 7, p. 3. Warrell,A(2012). Mobil Oil, Committee Hansard, Canberra, 30 November 2012, p. 4. Michael P (2012). Shell, Committee Hansard, Canberra, 30 November 2012, p. 21 Smith, G (2012). Caltex, Committee Hansard, Canberra, 30 November 2012, p. 31. AIP (2011). Downstream Petroleum 2011, p. 3. Australian Government (2012). Energy White Paper 2012, Australias energy transformation, p. 126. Caltex, 2017. Retrieved on 27/4/2017 from Caltex: https://www.caltex.com.au/find-a-caltex

Friday, November 29, 2019

Virtual Lesson Course Design and Teaching Online

Introduction Teaching career is one of those where people have to improve their quality often considering the requirements and standards set by the government. It is not always easy to create a unit according to which students are free to match their skills, knowledge, and interests with the activities promoted at classrooms (Beatly National Research Council, 2008).Advertising We will write a custom assessment sample on Virtual Lesson Course Design and Teaching Online specifically for you for only $16.05 $11/page Learn More In this paper, a K-12 content standard for social studies in high schools of California will be taken into consideration to encourage the best achievements for each student. What has to be done is a clear definition of student’s skills, knowledge, and concepts and apply them accordingly at the required Grade Ten. The project aims at outlining a week-long unit that is based on the Internet technologies’ use and direct pa rticipation of the instructor in the vast majority of students’ activities. The point is that students come to the courses with absolutely various levels of background knowledge (DiGiano, Goldman, Chorost, 2008), and it seems to be rather challenging to consider all needs and requirements under the same conditions. This is why a unit has to be developed taken into account a number of factors such as student interests and skills, instructor’s attitude, available technologies, and timing frames. Week-Long Unit Explanation The outline of the unit under analysis is rather simple and clear to the instructor as well as to the students. Unit Title: World History through the Internet Unit purpose: To help students study better the world history and focus on the events which took place between the 18th and 21st centuries including the two World Wars and American experience in country’s improvement and stabilization. The students will learn how to use the Internet source s to find more captivating details about the topic.Advertising Looking for assessment on education? Let's see if we can help you! Get your first paper with 15% OFF Learn More Unit Subject: Social Science and History Grade: 10 Time: 50 minutes each day (one week-long unit) Unit Peculiarities: History-Social Science Content Standards for California schools for the Tenth Grade are taken into considered; Students focus on the analysis of the historical events, abilities to participate in discussions, explanation, descriptions, etc. Outline Related to the Standard Relation of ethical issues to the development of the Western political ideas Comparison of revolutions in different countries; Analysis of the effects of Industrial Revolution in the USA, France, England, etc. Evaluation of the global changes in several countries; The First World War causes and effects: analysis; Investigations concerning the World War Second; Attention to the nation-building process in the wor ld; Research of the countries’ integrations and the development of technologies; Evaluation of the achievements observed during the course. Unit Structure The peculiar feature of the chosen unit structure is that it involves students in a variety of activities at the same time. As soon as the instructor introduces each member of the group (Boettcher Conrad, 2010), he/she offers new material, makes students get involved into searching activities, and promotes students’ participation in discussions which are based on the information found. It is not for the instructor to inform student but what is more important is to make students believe that different technologies are appropriate for improving students’ knowledge.Advertising We will write a custom assessment sample on Virtual Lesson Course Design and Teaching Online specifically for you for only $16.05 $11/page Learn More The instructor offers a number of assignments which have t o be performed in groups that also promotes the idea of competition and the desire to demonstrate better skills in searching, cooperating, and discussing (Ko Rossen, 2010). Students have to be encourage to develop into the offered learning environment and introduce the strategies which are more effective under the created conditions. The main advantage of the unit structure is that flexibility in thinking is appreciated. Video or audio conferencing (Dawley, 2007) are chosen as the main means of communication, still, chat are also appropriate for the chosen unit. Lesson Outlines As a rule, the outlines of the online lessons have to be similar so that the students as well as the instructor do not spend much time of learning the peculiarities of the new form of education. Students have to learn one particular way of how the material is offered and the discussions are organized to focus deeper on the content of the lesson but not on its structure. The example of the outline given below must be implemented to all the lessons of the particular unit. Students are provided with the topic for discussion and the reasons of why the chosen theme is interesting and important in education; Students get the worksheets on the basis of which the lesson will be developed; Students share their background knowledge and their wishes concerning what kind of knowledge may be gained; The instructor offers the list of readings which are required and encourages students to make use of various Internet sources which are appropriate for the course; Discussions take place as soon as the task is given; however, the discussions are based on the material given the day before so that the students are able to prepare; The instructor may improve the discussions to promote better understanding of the topic; Students have to share their opinions about the theme discussed and the methods used to disclose the topic; The instructor should conclude the achievements of the discussion and the skills gained by the students (lesson assessment is required); Possible improvements for future. One Fully Developed Lesson In this part of the paper, one lesson will be fully developed to explain the techniques and approaches which have to be used by the instructor. There are three main aspects which should be taken into consideration: content of the lesson, student interest, and possibilities. The description of the second lesson in a weak devoted to the Industrial Revolution will be offered. Lesson Objectives To understand the importance of the Industrial Revolution; To promote the use of different sources of information to gather the necessary material for discussions. Requirements Internet access; Pencils and paper for students to make notes; Web cameras for videoconferencing; Online books and notes. Evaluation of skills What do students know about the Industrial Revolution? What do students want to know about the chosen topic? What methods do students prefer to search for the m aterial? Lesson Plan The lesson begins with the discussion of the topic and the necessity to learn it. The Industrial Revolution in the middle of the 18th century changes the world in a variety of ways (Ross, 2008), and the students should know more about this period of time to know which methods were used and which outcomes were expected. Students have to be involved into the discussion: the instructor admits that in the middle of the 18th century, children did not find it necessary to visit schools and get appropriate education (Pierce, 2005), and students have to give as many reasons as possible for why such neglecting of education took place. Students are divided into the groups and discuss different spheres of life which underwent certain changes due to the Industrial Revolution. Pros and cons of the revolution are identified as well as the emergence of capitalism is considered as a dominant issue in the middle of the 18th century (â€Å"History-Social Science Content Standa rds for California Public Schools†, 2000). Students share their personal opinions about the role of the Industrial Revolution: it is not enough to introduce some general facts which are well-known, what students have to do is to prove that the revolution influenced human life and the ways of how people could develop business in different countries. Video conferencing takes place to ask questions, give answers, develop the theme under analysis, and improve personal knowledge about the Industrial Revolution in different countries. It is a luck in case the class consists of the students from different countries so that they can share their personal ideas and the impact of the revolution of their countries. The instructor offers the lesson assessment within the frames of which students are free to demonstrate the level of gained knowledge. Students are assigned to create PowerPoint presentations disclosing one of the aspects of the revolution. Students evaluate their achievements by means of audio conferencing with the tutor and discuss the improvements which are required. Media/ Technologies Used in the Project The success of the virtual course depends on the properly chosen technologies and media sources with the help of which the communication between the instructor and students may be developed. Communication systems serve as the most frequently used media that promotes the learning process implementation. Within a short period of time, media becomes a dominant factor in learning online (Anderson, 2008). Microsoft Office, Media Player, and Adobe Reader are the main programs which have to be available for the students so that they can easily read the instructions sent and perform their tasks accordingly. Skype is the program that may help to develop video and audio conferences any time for free.Advertising Looking for assessment on education? Let's see if we can help you! Get your first paper with 15% OFF Learn More The only point that has to be discussed at the beginning of the course is the technologies which may be used. If the vast majority of students as well as the instructor support the idea of Skype and some discussion boards, all the students have to use the same media. Web 2.0. Technology Web 2.0 is one of the newest propositions for the Internet users to improve their online communication and writing. As a rule, this technology supports numerous blogs, wikis, and social networking by means of which people are free to talk to each other (Solomon Schrum, 2007). In the course under analysis, the Web 2.0 technology such as wikis is offered to be used. Wikis are appropriate for a number of projects which promote several people to write, create, or revise in one team. With the help of this technology, it is possible to observe the recent changes and contribute the development of the topic. Under the chosen technology, the instructor creates a task and allows students answering the questio ns and developing the topic. Wikis do not take much place on computers and it is easy to understand how to use its services. The students should spend several minutes to learn the main aspects of the program and start using it. Pedagogical Approaches and Their Justification The chosen online learning process may be considerably improved by properly chosen pedagogical approaches. Some of them are given below: Behavioral perspective aims at developing appropriate skills of students to achieve the necessary behavioral outcomes. Students should understand that some form of control is required for the chosen form of education, and the instructor has to introduce it. The justification of this approach lies into the fact that even online learning has to correspond to certain norms, rules, and standards. And this approach as nothing else helps the instructor to choose the most effective ways of organizing student work online. Instructional perspective helps the instructor to organize the activities for the whole group: each step has to be properly weighted and each idea has to be justified. This approach is justified due to the required order of steps taken. A person has to understand the logic of personal activities and explain the necessary order to the students, and the peculiarities of the chosen approach will help to take the right direction. Social constructivism is the final approach to be used in pedagogy that promotes the development of the required learning environment and students’ participation in discussions. The peculiar feature of this approach is that online learning is based on numerous technologies and media. The offered approach will show the right way of how to organize online communication between the students who participate in discussion. Unit Assessment There are several methods of how unit assessment may be organized. One of the most frequently used is writing essays. The instructor asks to create a project that will help to under stand how successful each student in learning the new material and using the technologies offered. The chosen content of the unit is easy to combine with the media used. It is possible to discuss a certain historic even studied and evaluate the conditions under which the material was learnt. Online quizzes and some questions may also attract students’ attention. The following example of the quiz is possible to organize by means of the available Web 2.0 technology. The instructor creates a question and points out the name who has to answer it; then, the student who answers the question creates a new question on the same topic and asks another student to answer it. As soon as all students and the instructor participate in the quiz, they have to evaluate each question and answer and give the points. A person who gets more points gets a high grade and may omit other types of assessment. Such activity will promote the development of students’ imagination and the desire to d o their best. Finally, the students are questioned about the quality of the course offered and the ideas of how further courses may be improved. It is very important to consider students’ opinions in order to provide them with the best ideas, material, and knowledge. Conclusion In general, the success of the evaluated unit is predetermined by a variety of factors. The point is that both the instructor and the students have to be involved into the learning process. The way of how the instructor organizes students’ activities and the ideas offered by the students during the discussions determine the level of the course success. This is why it is useless to find the main person who is responsible for the course organization but try to choose the best activities to introduce an interesting and educative unit. Reference List Anderson, T. (2008). The theory and practice of online learning. Edmonton: Athabasca University Press. Beatly, A. National Research Council. (2008). A ssessing the role of K-12 academic standards in states: Workshop summary. Washington: National Academies Press. Boettcher, J.V. Conrad, R.M. (2010). The online teaching survival guide: Simple and practical pedagogical tips. Hoboken: John Wiley and Sons. Dawley, L. (2007). The tools for successful online teaching. Hershey: Idea Group Inc. DiGiano, C., Goldman, S.V., Chorost, M. (2008). Educating learning technologies designers: Guiding and inspiring creators of innovative educational tools. New York: Taylor Francis. â€Å"History-social science content standards for California public schools, kindergarten through grade twelve.† (2000). California State Board of Education. Retrieved from https://www.cde.ca.gov/be/st/ss/documents/histsocscistnd.pdf. Ko, S. Rossen, S. (2010). Teaching online: A practical guide. New York: Taylor Francis. Pierce, A. (2005). The Industrial Revolution. Edina: ABDO. Ross, S. (2008). The Industrial Revolution. London: Evans Brothers. Solomon, G. Schrum, L. (2007). Web 2.0.: New tools, new schools. Suite: ISTE. This assessment on Virtual Lesson Course Design and Teaching Online was written and submitted by user Miranda Delaney to help you with your own studies. You are free to use it for research and reference purposes in order to write your own paper; however, you must cite it accordingly. You can donate your paper here.

Monday, November 25, 2019

buy custom Auditory Processing Disorder essay

buy custom Auditory Processing Disorder essay Symptoms of Auditory Processing Disorder. People or children with this disorder usually experience trouble with remembering information which was delivered to them orally and besides that they have issues with paying attention therefore, information which is presented visually is well processed than oral information. They fail to receive information that is presented simultaneously in a number of ways. Such people are not able to remember multiple directions that were given orally because they can only remember one thing at a given time. They generally have underdeveloped listening skills therefore if the information has to be grasped well the personal passing the information needs to speak slowly. Persons with Auditory Processing Disorders take a long period to process verbal information. Such people are not fond of places or locations that usually have background noises like bars or other social places. They often prefer written information over verbal or oral information. At times their behavior may not be what is expected by many for instance when they try to fill the missing gaps through guessing. Manifestation of this disorder is manly in relation to sound for instance the direction of a specific sound, difficulties in telling the difference between the perceived sounds as well as aligning the various sounds to meaningful information. Confusion of sounds is common amongst people of this condition. Most of the times they may perceive some words but fail to say them this occurs as a result of poor connectivity in the said words making it difficult in getting the intended meaning. For these reason such a person may fail to see the sense in the words that people speak to them because of the missing links as a result of procession problems. Children with such complication often fail to get the meaning of the perceived information. They only realize that a word was spoken and though one may try to repeat the exact word they may not get the meaning (Katz, Stecker and Henderson, 1992). Backgrounds noise from the television or social places making it impossible for them to perceive and understand the spoken words. They often experience problems with telephone communication because of the low quality of the sound. Therefore telephones are not the best way of passing information to such people. Problems in receiving information that is passed over the telephone is associated with poor signal as well as intermittent sounds which may be chopping the words that the other person is speaking. Most of the people with auditory procession problems have perfect or sensitive vision which is perceived by many as a cooping strategy. They are particularly good at reading lips, getting the meaning through eye contact as well as body language. Such mechanisms usually help them to compensate their processor issues. The challenge is that this ability is only limited to face to face communication and is not of any importance to communication that is done over the phone. Some of the other characteristics that are not very specific include general shyness and quietness. At times they tend to withdraw from the main society because of the communication problem. Children who have such problems may experience humiliation at school because of lack of understanding by their classmates. Auditory processing disorder has negative implications to ones academics as well as social life because acquisition on knowledge will be difficult when one is not in apposition to process the necessary information and same applys to social interaction. Such people tend to isolate themselves because of fear of intermediation; they may fail to socialize because of their communication problem. Childrens education is tempered with when early diagnosis and treatment is not done. Adults are prone to interpersonal relationship issues that might be persistent because of the barrier to effective communication (Bellis, 2003). Buy custom Auditory Processing Disorder essay

Thursday, November 21, 2019

Strategy in the World Package Delivery Business Essay

Strategy in the World Package Delivery Business - Essay Example The essay "Strategy in the World Package Delivery Business" discusses the relationship between the planning and strategy in the world package delivery business. There is a direct relationship between planning and strategy since plans are made to identify goals (organizational or functional) and strategies are designed to achieve these identified goals. In this case scenario (Jones & George, 2007), FedEx planned to address competition from UPS by identifying an opportunity in the overnight delivery niche even by charging a premium price. As emphasized in Operations Strategy and Competitiveness, â€Å"the business strategy of FedEx, the world’s largest provider of expedited delivery services, is to compete on time and dependability of deliveries. The operations strategy of FedEx developed a plan for resources to support its business strategy. To provide the speed of delivery, FedEx acquired its own fleet of airplanes. To provide dependability of deliveries, FedEx invested in a sophisticated bar code technology to track all packages†. To compete with FedEx and DHL, UPS must review and evaluate the strategies of both organizations to gauge their strengths and weaknesses. Using this information as inputs, UPS must then identify opportunities and threats in the world package delivery business to enable them to tap the opportunities and address the threats or risks, as required. Using their core competencies in using their tracking and information system; as well as in logistics, specifically in meeting delivery schedules faster.